MyBioSource.com's JAG1 Antibody (C-term) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Flow Cytometry, and Western Blot. The JAG1 Antibody (C-term) was generated using AGS, AHD, CD339, JAG1, and Jagged 1 as the antigen and it reacts with Human, and Rat.
Description
The jagged 1 protein encoded by JAG1 is the human homolog
of the Drosophilia jagged protein. Human jagged 1 is the ligand
for the receptor notch 1, the latter a human homolog of the
Drosophilia jagged receptor notch. Mutations that alter the jagged
1 protein cause Alagille syndrome. Jagged 1 signalling through
notch 1 has also been shown to play a role in hematopoiesis